Guinea Pig Pancreas Morphology: intracisternal granules

Creator:
Palade, George E
Published/Created:
New Haven, CT
Yale University School of Medicine
10/27/1954
Physical Description:
3.25 in. x 4 in.
Notes:
3.25 in. x 4 in. Lantern Slides
Original Magnification: x13,000
Intracisternal granules with an electron density equal to that of zymogen granules are found in the RER cisternae of animals fed after starvation or after intense in vitro stimulation with secretagogues. They may reflect the Unfolded Protein Response following rapid synthesis of proteins that outstrips the ability of the quality control system to keep up with folding of proteins for export from the RER.
Topics:
Guinea Pig Pancreas Morphology
Topics:
Jamieson, James D
Genre:
transmission electron micrograph
Format:
Image
Content Type:
Prints & Photographs
Rights:
The use of this image may be subject to the copyright law of the United States (Title 17, United States Code) or to site license or other rights management terms and conditions. The person using the image is liable for any infringement
Yale Community Only
Access Restrictions:
Public
Yale Collection:
Yale University School of Medicine, Department of Cell Biology
Digital Collection:
George E. Palade Electron Microscopy Slide Collection
Citation:
See Palade, G.E. 1956. Intracisternal granules in the exocrine cells of the pancreas. J. Biochem. Biophys. Cytol. 2:417-422.
OID:
15817855
PID:
digcoll:2795311