New Haven, CT Yale University School of Medicine 5/1/1961
3.25 in. x 4 in.
3.25 in. x 4 in. Lantern Slides Original Magnification: x10,000 Cell fractionation confirmed that newly synthesized acinar cell secretory proteins moved from the RER to the periphery of the Golgi in the lumen of a smooth-surfaced membrane bounded compartment. This paper also describes the pancreatic slice system and the pulse-chase protocol used to label newly synthesized secretory proteins with radioactive leucine. The micrograph shows smooth microsomes obtained from the top band in the photograph of sucrose density gradient.
Jamieson, James D
transmission electron micrograph
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Yale University School of Medicine, Department of Cell Biology
George E. Palade Electron Microscopy Slide Collection
See Jamieson, J.D., and Palade, G.E. Intracellular transport of secretory proteins in the pancreatic exocrine cell. I. Role of the peripheral elements of the Golgi complex. J. Cell Biol. 34:577-596, 1967.
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